Which of the following is a low molecular weight heparin used for preventing DVT/PE after surgery?

Which of the following is a low molecular weight heparin used for preventing DVT/PE after surgery?

• A. Heparin
• B. Enoxaparin
• C. Warfarin
• D. Fondaparinux

Answer: (B)

Low molecular weight heparins are preferred for preventing DVT/PE after surgery because they provide reliable anticoagulation with more predictable effects and don't require routine monitoring. Enoxaparin is a classic LMWH used for post-op DVT and PE prophylaxis. It mainly inhibits factor Xa via antithrombin III and has predictable pharmacokinetics, so dosing is straightforward and often can be given subcutaneously on an outpatient basis. Unfractionated heparin is not LMWH and typically requires monitoring and IV administration. Warfarin is an oral agent with a delayed onset and is not suitable for immediate post-op prophylaxis. Fondaparinux is a synthetic Xa inhibitor but is not a heparin; the question specifically asks for a low molecular weight heparin, which points to enoxaparin.

Low molecular weight heparins are preferred for preventing DVT/PE after surgery because they provide reliable anticoagulation with more predictable effects and don't require routine monitoring. Enoxaparin is a classic LMWH used for post-op DVT and PE prophylaxis. It mainly inhibits factor Xa via antithrombin III and has predictable pharmacokinetics, so dosing is straightforward and often can be given subcutaneously on an outpatient basis. Unfractionated heparin is not LMWH and typically requires monitoring and IV administration. Warfarin is an oral agent with a delayed onset and is not suitable for immediate post-op prophylaxis. Fondaparinux is a synthetic Xa inhibitor but is not a heparin; the question specifically asks for a low molecular weight heparin, which points to enoxaparin.