Which statement about inhaled corticosteroids (ICS) with Fluticasone is true?

Which statement about inhaled corticosteroids (ICS) with Fluticasone is true?

• A. Acts as a bronchodilator within minutes
• B. Decreases airway inflammation; can cause thrush; rinse mouth after use
• C. Used only for rescue therapy
• D. Increases mucous production

Answer: (B)

Inhaled corticosteroids like fluticasone are anti-inflammatory medicines used for long-term control of asthma, not for immediate relief. They work by reducing airway inflammation and hyperresponsiveness, which improves symptoms over time. Because they’re not bronchodilators, they don’t provide quick relief within minutes. A common local side effect is oral candidiasis (thrush) due to the steroid's effect in the oropharynx, which is why rinsing the mouth after each use helps prevent it. They’re used as maintenance therapy, not rescue therapy, and they don’t increase mucus production; reducing inflammation can actually help decrease mucus over time. Therefore, the statement that reflects their action and typical side effects is that they decrease airway inflammation, can cause thrush, and require rinsing after use.